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Excessive BP at Night time, Alzheimer’s Threat Might Rise, Too

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High BP at Night, Alzheimer's Risk May Rise, Too

By Robert Preidt

HealthDay Reporter

TUESDAY, Feb. 9, 2021 (HealthDay Information) — Older males whose blood pressure rises at evening could also be at elevated danger for Alzheimer’s disease, a brand new examine suggests.

Blood strain modifications over 24 hours. It usually goes up throughout the day and dips at nighttime. However some folks have an reverse sample, which is named reverse dipping.

“The evening is a vital interval for mind well being. For instance, in animals, it has beforehand been proven that the mind clears out waste merchandise throughout sleep, and that this clearance is compromised by irregular blood strain patterns,” examine co-author Christian Benedict mentioned. He is an affiliate professor of neuroscience at Uppsala College in Sweden.

“For the reason that evening additionally represents a vital time window for human mind well being, we examined whether or not too high blood pressure at evening, as seen in reverse dipping, is related to the next dementia danger in older males,” Benedict mentioned in a college information launch.

Blood strain is one in all a number of elements that may have an effect on the chance of Alzheimer’s and different forms of dementia.

Benedict and colleagues analyzed information from 1,000 older Swedish males who had been adopted for as much as 24 years. The boys had been of their early 70s when researchers started monitoring them.

“The chance of getting a dementia prognosis was 1.64 instances greater amongst males with reverse dipping in comparison with these with regular dipping. Reverse dipping primarily elevated the chance of Alzheimer’s illness, the commonest type of dementia,” mentioned examine co-author Xiao Tan, a postdoctoral fellow within the college’s neuroscience division.

The examine was printed Feb. 8 within the journal Hypertension.

As a result of the examine group consisted solely of older males, “our outcomes should be replicated in older ladies,” Benedict famous.

The examine authors mentioned a subsequent step on this line of analysis can be to look at whether or not taking blood pressure-lowering medicine might scale back older males’s danger of Alzheimer’s illness.


Extra info

The U.S. Nationwide Institute on Ageing has extra about Alzheimer’s risk factors.


SOURCE: Uppsala College, information launch, Feb. 8, 2021



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